KEYNOTE-522: Triple-Negative Breast Cancer (TNBC) Treatment Protocol
This video explains the KEYNOTE-522 treatment plan for patients with triple-negative breast cancer (TNBC) in a clear and simple way. We cover:
What KEYNOTE-522 is and why this treatment approach was developed
Treatment plan:
Neoadjuvant therapy (before surgery):
Paclitaxel + Carboplatin + Pembrolizumab → weekly for 12 weeks
Followed by AC chemotherapy (Adriamycin + Cyclophosphamide) + Pembrolizumab → every 3 weeks × 4 cycles
Surgery
Adjuvant therapy (after surgery): Pembrolizumab continues for up to 9 cycles
Tips for managing side effects and staying on track during treatment
Our goal is to help you understand your treatment, know what to expect, and feel informed and supported throughout your TNBC journey.